Job Posting specifies minimum and preferred requirements. Usually, in big companies, skill in a category is assumed to be transferrable to another provide you have righ mindset. If you are expert in one area only and would like to stick to it, please mention that in your interview. Mostly there are interviews. First, by HR to go through minimum and specific requirements. Sometimes the years of experience do not translate to expertise. Either specify that your 2yrs intense experience is as good as 5yrs or mention that even though you worked on a particular technology for 5yrs, you are passionate about other technology and would like to expand on it. Ultimately, you want the job satisfaction. Second and Third interviews are with peers and supervisors.